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Langefeld, Carl
One or more keywords matched the following items that are connected to Langefeld, Carl
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Academic Article Association of an IL-1A 3'UTR polymorphism with end-stage renal disease and IL-1 alpha expression.
Academic Article Insulin sensitivity, insulin secretion, and abdominal fat: the Insulin Resistance Atherosclerosis Study (IRAS) Family Study.
Academic Article Age-stratified heritability estimation in the Framingham Heart Study families.
Academic Article Ordered subset analysis in genetic linkage mapping of complex traits.
Academic Article Identification of quantitative trait loci for glucose homeostasis: the Insulin Resistance Atherosclerosis Study (IRAS) Family Study.
Academic Article Association analysis of the plasminogen activator inhibitor-1 4G/5G polymorphism in Hispanics and African Americans: the IRAS family study.
Academic Article Association of protein tyrosine phosphatase 1B gene polymorphisms with measures of glucose homeostasis in Hispanic Americans: the insulin resistance atherosclerosis study (IRAS) family study.
Academic Article A genome scan for fasting insulin and fasting glucose identifies a quantitative trait locus on chromosome 17p: the insulin resistance atherosclerosis study (IRAS) family study.
Academic Article Pericardial and visceral adipose tissues measured volumetrically with computed tomography are highly associated in type 2 diabetic families.
Academic Article Genetic analysis of HNF4A polymorphisms in Caucasian-American type 2 diabetes.
Academic Article P-selectin gene haplotype associations with albuminuria in the Diabetes Heart Study.
Academic Article Association of protein tyrosine phosphatase-N1 polymorphisms with coronary calcified plaque in the Diabetes Heart Study.
Academic Article Genetic mapping of disposition index and acute insulin response loci on chromosome 11q. The Insulin Resistance Atherosclerosis Study (IRAS) Family Study.
Academic Article A functional polymorphism in the lymphotoxin-alpha gene is associated with carotid artery wall thickness: the Diabetes Heart Study.
Academic Article Heritability and expression of C-reactive protein in type 2 diabetes in the Diabetes Heart Study.
Academic Article A leucine repeat in the carnosinase gene CNDP1 is associated with diabetic end-stage renal disease in European Americans.
Academic Article FcalphaRI (CD89) alleles determine the proinflammatory potential of serum IgA.
Academic Article The association between innate immunity gene (IRAK1) and C-reactive protein in the Diabetes Heart Study.
Academic Article Associations of adiponectin with body fat distribution and insulin sensitivity in nondiabetic Hispanics and African-Americans.
Academic Article Variants of the transcription factor 7-like 2 (TCF7L2) gene are associated with type 2 diabetes in an African-American population enriched for nephropathy.
Academic Article Comprehensive evaluation of the estrogen receptor alpha gene reveals further evidence for association with type 2 diabetes enriched for nephropathy in an African American population.
Academic Article Polymorphisms near SOCS3 are associated with obesity and glucose homeostasis traits in Hispanic Americans from the Insulin Resistance Atherosclerosis Family Study.
Academic Article Genome screen in familial intracranial aneurysm.
Academic Article Association of SSTR2 polymorphisms and glucose homeostasis phenotypes: the Insulin Resistance Atherosclerosis Family Study.
Academic Article Identification of IRAK1 as a risk gene with critical role in the pathogenesis of systemic lupus erythematosus.
Academic Article High-density genotyping of STAT4 reveals multiple haplotypic associations with systemic lupus erythematosus in different racial groups.
Academic Article Association of 25-hydroxyvitamin D with blood pressure in predominantly 25-hydroxyvitamin D deficient Hispanic and African Americans.
Academic Article A polymorphism within IL21R confers risk for systemic lupus erythematosus.
Academic Article Variant in the 3' region of the IkappaBalpha gene associated with insulin resistance in Hispanic Americans: The IRAS Family Study.
Academic Article Comparative analyses of single-nucleotide polymorphisms in the TNF promoter region provide further validation for the vervet monkey model of obesity.
Academic Article Chromosome 7p linkage and association study for diabetes related traits and type 2 diabetes in an African-American population enriched for nephropathy.
Academic Article Genetic factors predisposing to systemic lupus erythematosus and lupus nephritis.
Academic Article Analysis of candidate genes on chromosome 20q12-13.1 reveals evidence for BMI mediated association of PREX1 with type 2 diabetes in European Americans.
Academic Article Molecular basis of a linkage peak: exome sequencing and family-based analysis identify a rare genetic variant in the ADIPOQ gene in the IRAS Family Study.
Academic Article The role of genetic variation near interferon-kappa in systemic lupus erythematosus.
Academic Article Correlates of coronary artery calcified plaque in blacks and whites with type 2 diabetes.
Academic Article Single-nucleotide polymorphisms in the TNF gene are associated with obesity-related phenotypes in vervet monkeys.
Academic Article Association of a functional variant downstream of TNFAIP3 with systemic lupus erythematosus.
Academic Article Differential genetic associations for systemic lupus erythematosus based on anti-dsDNA autoantibody production.
Academic Article Genomewide linkage scan for diabetic renal failure and albuminuria: the FIND study.
Academic Article Common variants in the periostin gene influence development of atherosclerosis in young persons.
Academic Article Association of genetic variants in complement factor H and factor H-related genes with systemic lupus erythematosus susceptibility.
Academic Article Sickle cell trait is not independently associated with susceptibility to end-stage renal disease in African Americans.
Academic Article Lupus-associated causal mutation in neutrophil cytosolic factor 2 (NCF2) brings unique insights to the structure and function of NADPH oxidase.
Academic Article Evaluation of TRAF6 in a large multiancestral lupus cohort.
Academic Article Exploring differences in adiposity in two U.S. Hispanic populations of Mexican origin using social, behavioral, physiologic and genetic markers: the IRAS Family Study.
Academic Article Apolipoprotein L1 gene variants associate with hypertension-attributed nephropathy and the rate of kidney function decline in African Americans.
Academic Article Impact of genetic ancestry and sociodemographic status on the clinical expression of systemic lupus erythematosus in American Indian-European populations.
Academic Article Estimating the contributions of rare and common genetic variations and clinical measures to a model trait: adiponectin.
Academic Article Informed conditioning on clinical covariates increases power in case-control association studies.
Academic Article Risk factors for intracerebral hemorrhage differ according to hemorrhage location.
Academic Article Transferability and fine mapping of type 2 diabetes loci in African Americans: the Candidate Gene Association Resource Plus Study.
Academic Article Heritability of carotid artery intima-medial thickness in type 2 diabetes.
Academic Article Genetic epidemiology of insulin resistance and visceral adiposity. The IRAS Family Study design and methods.
Academic Article Pleiotropy and heterogeneity in the expression of atherogenic lipoproteins: the IRAS Family Study.
Academic Article Age-stratified QTL genome scan analyses for anthropometric measures.
Academic Article Linkage of the metabolic syndrome to 1q23-q31 in Hispanic families: the Insulin Resistance Atherosclerosis Study Family Study.
Academic Article Preventive foot-care practices among adults with diabetes in North Carolina, 1997 to 2001.
Academic Article Genetic analysis of adiponectin and obesity in Hispanic families: the IRAS Family Study.
Academic Article The impact of pedigree structure on heritability estimates for pulse pressure in three studies.
Academic Article Multilocus and interaction-based genome scan for alcoholism risk factors in Caucasian Americans: the COGA study.
Academic Article A comparison of risk factors for calcified atherosclerotic plaque in the coronary, carotid, and abdominal aortic arteries: the diabetes heart study.
Academic Article Association of the estrogen receptor-alpha gene with the metabolic syndrome and its component traits in African-American families: the Insulin Resistance Atherosclerosis Family Study.
Academic Article Association of TCF7L2 gene polymorphisms with reduced acute insulin response in Hispanic Americans.
Academic Article Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci.
Academic Article Quantitative trait analysis of type 2 diabetes susceptibility loci identified from whole genome association studies in the Insulin Resistance Atherosclerosis Family Study.
Academic Article Association analysis in african americans of European-derived type 2 diabetes single nucleotide polymorphisms from whole-genome association studies.
Academic Article Genetic and environmental determinants of 25-hydroxyvitamin D and 1,25-dihydroxyvitamin D levels in Hispanic and African Americans.
Academic Article Association of the Kir6.2 E23K variant with reduced acute insulin response in African-Americans.
Academic Article Identification of IFRD1 as a modifier gene for cystic fibrosis lung disease.
Academic Article INSIG2 SNPs associated with obesity and glucose homeostasis traits in Hispanics: the IRAS Family Study.
Academic Article Evaluation of DLG2 as a positional candidate for disposition index in African-Americans from the IRAS Family Study.
Academic Article The relationship between smoking and replicated sequence variants on chromosomes 8 and 9 with familial intracranial aneurysm.
Academic Article Juvenile idiopathic arthritis and HLA class I and class II interactions and age-at-onset effects.
Academic Article The non-muscle Myosin heavy chain 9 gene (MYH9) is not associated with lupus nephritis in African Americans.
Academic Article Resequencing and analysis of variation in the TCF7L2 gene in African Americans suggests that SNP rs7903146 is the causal diabetes susceptibility variant.
Academic Article Association of PNPLA3 with non-alcoholic fatty liver disease in a minority cohort: the Insulin Resistance Atherosclerosis Family Study.
Academic Article Apolipoprotein L1 nephropathy risk variants associate with HDL subfraction concentration in African Americans.
Academic Article Preferential transmission of genetic risk variants of candidate loci at 6p21 from asymptomatic grandparents to mothers of children with neonatal lupus.
Academic Article Analysis of autosomal genes reveals gene-sex interactions and higher total genetic risk in men with systemic lupus erythematosus.
Academic Article Genetic risk assessment of type 2 diabetes-associated polymorphisms in African Americans.
Academic Article Identification of IRF8, TMEM39A, and IKZF3-ZPBP2 as susceptibility loci for systemic lupus erythematosus in a large-scale multiracial replication study.
Academic Article Association of APOL1 variants with mild kidney disease in the first-degree relatives of African American patients with non-diabetic end-stage renal disease.
Academic Article Levels of free fatty acids (FFA) are associated with insulin resistance but do not explain the relationship between adiposity and insulin resistance in Hispanic Americans: the IRAS Family Study.
Academic Article Association of two independent functional risk haplotypes in TNIP1 with systemic lupus erythematosus.
Academic Article Fine mapping of Xq28: both MECP2 and IRAK1 contribute to risk for systemic lupus erythematosus in multiple ancestral groups.
Academic Article Burden of risk alleles for hypertension increases risk of intracerebral hemorrhage.
Academic Article Genome-wide association study of intracranial aneurysms confirms role of Anril and SOX17 in disease risk.
Academic Article Polymorphisms in the Selenoprotein S gene and subclinical cardiovascular disease in the Diabetes Heart Study.
Academic Article Usefulness of biventricular volume as a predictor of mortality in patients with diabetes mellitus (from the Diabetes Heart Study).
Academic Article Genetic analysis of haptoglobin polymorphisms with cardiovascular disease and type 2 diabetes in the Diabetes Heart Study.
Concept Kruppel-Like Transcription Factors
Concept Likelihood Functions
Concept Ikaros Transcription Factor
Concept Sp3 Transcription Factor
Concept STAT4 Transcription Factor
Concept rac1 GTP-Binding Protein
Concept Vitamin D-Binding Protein
Concept Sex Factors
Concept Rheumatoid Factor
Concept Calcium-Binding Proteins
Concept Fibroblast Growth Factors
Concept SOXF Transcription Factors
Concept Interferon Regulatory Factors
Concept Carrier Proteins
Concept TCF Transcription Factors
Concept Methyl-CpG-Binding Protein 2
Concept Complement Factor H
Concept Behavioral Risk Factor Surveillance System
Concept Core Binding Factor Alpha 3 Subunit
Concept Factor Analysis, Statistical
Concept Insulin Resistance
Concept Vascular Endothelial Growth Factor B
Concept Tumor Necrosis Factor-alpha
Concept Insulin-Secreting Cells
Concept Transforming Growth Factor beta1
Concept Time Factors
Concept Insulin
Concept Protein Binding
Concept Age Factors
Concept Hepatocyte Nuclear Factor 4
Concept TNF Receptor-Associated Factor 6
Concept DNA-Binding Proteins
Concept Transforming Growth Factor beta
Concept Factor XIII
Concept Transcription Factors
Concept Insulin-Like Growth Factor Binding Proteins
Concept Socioeconomic Factors
Concept Guanine Nucleotide Exchange Factors
Concept STAT1 Transcription Factor
Concept Insulin-Like Growth Factor Binding Protein 1
Concept Risk Factors
Concept Transcription Factor RelA
Concept RNA-Binding Proteins
Concept NFI Transcription Factors
Concept Insulin-Like Growth Factor Binding Protein 3
Academic Article Dense genotyping of immune-related disease regions identifies 14 new susceptibility loci for juvenile idiopathic arthritis.
Academic Article Association of SNPs in the UGT1A gene cluster with total bilirubin and mortality in the Diabetes Heart Study.
Academic Article The Ethnic/Racial Variations of Intracerebral Hemorrhage (ERICH) study protocol.
Academic Article Chromosome 2q31.1 associates with ESRD in women with type 1 diabetes.
Academic Article Apolipoprotein E, statins, and risk of intracerebral hemorrhage.
Academic Article Preferential binding to Elk-1 by SLE-associated IL10 risk allele upregulates IL10 expression.
Academic Article ABIN1 dysfunction as a genetic basis for lupus nephritis.
Academic Article JC polyoma virus interacts with APOL1 in African Americans with nondiabetic nephropathy.
Academic Article Genetic variants in selenoprotein P plasma 1 gene (SEPP1) are associated with fasting insulin and first phase insulin response in Hispanics.
Academic Article Genetic analysis of adiponectin variation and its association with type 2 diabetes in African Americans.
Academic Article Meta-analysis of genome-wide association studies in African Americans provides insights into the genetic architecture of type 2 diabetes.
Academic Article Genome-wide family-based linkage analysis of exome chip variants and cardiometabolic risk.
Academic Article Sclerostin is positively associated with bone mineral density in men and women and negatively associated with carotid calcified atherosclerotic plaque in men from the African American-Diabetes Heart Study.
Academic Article Insulin sensitivity and insulin clearance are heritable and have strong genetic correlation in Mexican Americans.
Academic Article End-stage renal disease in African Americans with lupus nephritis is associated with APOL1.
Academic Article Genetic risk score associations with cardiovascular disease and mortality in the Diabetes Heart Study.
Academic Article Complement factor H gene associations with end-stage kidney disease in African Americans.
Academic Article Heritability and genetic association analysis of cognition in the Diabetes Heart Study.
Academic Article Coding variants in nephrin (NPHS1) and susceptibility to nephropathy in African Americans.
Academic Article The ras responsive transcription factor RREB1 is a novel candidate gene for type 2 diabetes associated end-stage kidney disease.
Academic Article The IRF5-TNPO3 association with systemic lupus erythematosus has two components that other autoimmune disorders variably share.
Academic Article Infection after intracerebral hemorrhage: risk factors and association with outcomes in the ethnic/racial variations of intracerebral hemorrhage study.
Academic Article Heritability and genetic association analysis of neuroimaging measures in the Diabetes Heart Study.
Academic Article Lupus Risk Variant Increases pSTAT1 Binding and Decreases ETS1 Expression.
Academic Article Analysis of a cardiovascular disease genetic risk score in the Diabetes Heart Study.
Academic Article Meta-Analysis of Genome-Wide Association Studies Identifies Genetic Risk Factors for Stroke in African Americans.
Academic Article Rare Coding Variation and Risk of Intracerebral Hemorrhage.
Academic Article Monocyte Count and 30-Day Case Fatality in Intracerebral Hemorrhage.
Academic Article An Islet-Targeted Genome-Wide Association Scan Identifies Novel Genes Implicated in Cytokine-Mediated Islet Stress in Type 2 Diabetes.
Academic Article Genome-Wide Association and Trans-ethnic Meta-Analysis for Advanced Diabetic Kidney Disease: Family Investigation of Nephropathy and Diabetes (FIND).
Academic Article Deceased donor multidrug resistance protein 1 and caveolin 1 gene variants may influence allograft survival in kidney transplantation.
Academic Article Genome-Wide Association Study in an Amerindian Ancestry Population Reveals Novel Systemic Lupus Erythematosus Risk Loci and the Role of European Admixture.
Academic Article Prophylactic Antiepileptic Drug Use and Outcome in the Ethnic/Racial Variations of Intracerebral Hemorrhage Study.
Academic Article Preferential association of a functional variant in complement receptor 2 with antibodies to double-stranded DNA.
Academic Article APOL1 Genotype and Kidney Transplantation Outcomes From Deceased African American Donors.
Academic Article HLA-DRB1*11 and variants of the MHC class II locus are strong risk factors for systemic juvenile idiopathic arthritis.
Academic Article Plasma FGF23 and Calcified Atherosclerotic Plaque in African Americans with Type 2 Diabetes Mellitus.
Academic Article Tissue-Specific and Genetic Regulation of Insulin Sensitivity-Associated Transcripts in African Americans.
Academic Article Identification of a Systemic Lupus Erythematosus Risk Locus Spanning ATG16L2, FCHSD2, and P2RY2 in Koreans.
Academic Article Selecting SNPs informative for African, American Indian and European Ancestry: application to the Family Investigation of Nephropathy and Diabetes (FIND).
Academic Article Improved Performance of Dynamic Measures of Insulin Response Over Surrogate Indices to Identify Genetic Contributors of Type 2 Diabetes: The GUARDIAN Consortium.
Academic Article APOL1 renal-risk genotypes associate with longer hemodialysis survival in prevalent nondiabetic African American patients with end-stage renal disease.
Academic Article Trans-ethnic Meta-analysis and Functional Annotation Illuminates the Genetic Architecture of Fasting Glucose and Insulin.
Academic Article Relationships between measures of adiposity with subclinical atherosclerosis in patients with type 2 diabetes.
Academic Article Decreased SMG7 expression associates with lupus-risk variants and elevated antinuclear antibody production.
Academic Article Untreated Hypertension: A Powerful Risk Factor for Lobar and Nonlobar Intracerebral Hemorrhage in Whites, Blacks, and Hispanics.
Academic Article APOL1 Renal-Risk Variants Induce Mitochondrial Dysfunction.
Academic Article Analysis of Whole Exome Sequencing with Cardiometabolic Traits Using Family-Based Linkage and Association in the IRAS Family Study.
Academic Article Genetic architecture distinguishes systemic juvenile idiopathic arthritis from other forms of juvenile idiopathic arthritis: clinical and therapeutic implications.
Academic Article Novel Genetic Variants Associated With Increased Vertebral Volumetric BMD, Reduced Vertebral Fracture Risk, and Increased Expression of SLC1A3 and EPHB2.
Academic Article Genome-wide linkage and association analysis of cardiometabolic phenotypes in Hispanic Americans.
Academic Article Rare and low-frequency coding variants alter human adult height.
Grant Genetic Architecture of Obesity and Inflammation in Hispanic Americans
Grant Genetics of Juvenile Idiopathic Arthritis and Subtypes
Grant Exome Sequencing to Identify CVD Risk Variants in Hispanics & African Americans
Academic Article Bladder Capacity is a Biomarker for a Bladder Centric versus Systemic Manifestation in Interstitial Cystitis/Bladder Pain Syndrome.
Academic Article A genome-wide linkage and association analysis of imputed insertions and deletions with cardiometabolic phenotypes in Mexican Americans: The Insulin Resistance Atherosclerosis Family Study.
Academic Article Aggressiveness of care following intracerebral hemorrhage in women and men.
Academic Article Factors Considered by Clinicians when Prognosticating Intracerebral Hemorrhage Outcomes.
Academic Article Assessment of the interaction of age and sex on 90-day outcome after intracerebral hemorrhage.
Academic Article Variability in the Use of Platelet Transfusion in Patients with Intracerebral Hemorrhage: Observations from the Ethnic/Racial Variations of Intracerebral Hemorrhage Study.
Academic Article Genome-Wide Association Meta-Analysis Reveals Novel Juvenile Idiopathic Arthritis Susceptibility Loci.
Grant Genetics and the Microbiome in Anti-Ro Preclinical and Established Autoimmunity
Academic Article Genetic variants influencing elevated myeloperoxidase levels increase risk of stroke.
Academic Article Early-life environmental exposures interact with genetic susceptibility variants in pediatric patients with eosinophilic esophagitis.
Academic Article Association of Natural Killer Cell Ligand Polymorphism HLA-C Asn80Lys With the Development of Anti-SSA/Ro-Associated Congenital Heart Block.
Academic Article FGF23 Concentration and APOL1 Genotype Are Novel Predictors of Mortality in African Americans With Type 2 Diabetes.
Academic Article Adipose Tissue Transferrin and Insulin Resistance.
Academic Article Genome-wide association studies suggest that APOL1-environment interactions more likely trigger kidney disease in African Americans with nondiabetic nephropathy than strong APOL1-second gene interactions.
Academic Article Exome Sequencing Identifies Genetic Variants Associated with Circulating Lipid Levels in Mexican Americans: The Insulin Resistance Atherosclerosis Family Study (IRASFS).
Academic Article A plausibly causal functional lupus-associated risk variant in the STAT1-STAT4 locus.
Academic Article Metabolomics Identifies Distinctive Metabolite Signatures for Measures of Glucose Homeostasis: The Insulin Resistance Atherosclerosis Family Study (IRAS-FS).
Academic Article Genome-Wide Study of Subcutaneous and Visceral Adipose Tissue Reveals Novel Sex-Specific Adiposity Loci in Mexican Americans.
Academic Article Hypertension and intracerebral hemorrhage recurrence among white, black, and Hispanic individuals.
Academic Article Trans-Ethnic Mapping of BANK1 Identifies Two Independent SLE-Risk Linkage Groups Enriched for Co-Transcriptional Splicing Marks.
Academic Article Minority Patients are Less Likely to Undergo Withdrawal of Care After Spontaneous Intracerebral Hemorrhage.
Academic Article Brief Report: The Genetic Profile of Rheumatoid Factor-Positive Polyarticular Juvenile Idiopathic Arthritis Resembles That of Adult Rheumatoid Arthritis.
Academic Article Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes.
Academic Article Genetic Regulation of Enoyl-CoA Hydratase Domain-Containing 3 in Adipose Tissue Determines Insulin Sensitivity in African Americans and Europeans.
Academic Article Multiancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions.
Academic Article Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity.
Academic Article Association of Apolipoprotein E With Intracerebral Hemorrhage Risk by Race/Ethnicity: A Meta-analysis.
Academic Article The nuclear structural protein NuMA is a negative regulator of 53BP1 in DNA double-strand break repair.
Academic Article Latent autoimmunity across disease-specific boundaries in at-risk first-degree relatives of SLE and RA patients.
Academic Article GWAS and colocalization analyses implicate carotid intima-media thickness and carotid plaque loci in cardiovascular outcomes.
Academic Article Genome-wide enriched pathway analysis of acute post-radiotherapy pain in breast cancer patients: a prospective cohort study.
Academic Article The triglyceride to high-density lipoprotein cholesterol (TG/HDL-C) ratio as a predictor of insulin resistance, ß-cell function, and diabetes in Hispanics and African Americans.
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